Rhinovirus Infections

Rhinovirus Infections and Disease: Rethinking the Impact on Human Health and Disease provides a timely review of the impact of rhinovirus infections on human health. It identifies disease mechanisms related to the virus, human host, and environmental factors. This viewpoint allows us to look forward to the development of treatments for a virus for which treatment options are currently non-existent. The last two decades have seen an explosion in research revealing rhinovirus to be causative in a multitude of serious lower respiratory tract (LRT) conditions including bronchiolitis, pneumonia and life-threatening exacerbations. Over 150 genetically distinct rhinovirus subtypes have now been identified and diseases caused by rhinovirus infection affect millions of people of all ages in both developed- and developing-countries. By providing detailed insight into the multitude of this virus, host, and environmental factors that play into rhinovirus induced diseases, Rhinovirus Infections and Disease: Rethinking the Impact on Human Health and Disease explains the disease mechanisms and summarizes existing and developing therapeutic approaches for better research, diagnosis and potential treatments. Provides insight into viral diversity and identification of virulence factors, showing how the subtype of rhinovirus affect susceptibility to diseases and what the clinically important virulence determinants are Explores host and environmental factors, explaining how age, health status, genotype, lifestyle, and environment influence the outcome of a rhinovirus infection Covers vaccines and treatments, discussing the health burden associated with rhinovirus infections and the driving development of an increasing array of treatment approaches

keywords:

Science > Life Sciences > Biology, Science > Life Sciences, Rhinoviruses, Infectious & contagious diseases